Diagnosis & Disease Information

liver transplant

Liver From SARS-CoV-2 RNA-Positive Donor Successfully Transplanted in Child With ALGS

A pediatric patient with Alagille syndrome (ALGS) underwent a successful liver transplantation from a deceased asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-positive pediatric donor without evidence of viral transmission. In addition to this patient, 6 other patients with different diagnoses received organs from the same donor or a second pediatric donor who also…

Myasthenia Gravis

Surgery Is Safe in Most Elderly Patients With MG With Close Monitoring

Most elderly patients with myasthenia gravis (MG) “safely survive the perioperative period,” according to a new study published in Thoracic Cancer. These patients “benefit from surgery through individualized consideration,” the authors said. To assess the safety of surgery in patients with MG aged 65 years and over, a team of researchers from China analyzed perioperative…

COVID19

Case Report: Liver Transplantation in a Pediatric Patient With ALGS and COVID-19

Liver transplantation was successfully performed in a pediatric patient with Alagille syndrome (ALGS) and a concomitant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a case report recently published in Hepatology Research. The patient, a 3-year-old girl with liver cirrhosis, was admitted to a hospital for deceased-donor liver transplantation. As the patient’s liver…

surgeon tools

Domino Liver Transplantation From Val30Met hATTR Donors Appears Safe

Domino liver transplantation (DLT) from donors with hereditary transthyretin amyloidosis (hATTR) harboring the Val30Met mutation seems to be safe, despite frequent observations of cardiac abnormalities. “Recipients of DLT have significant cardiomyopathy mostly attributable to their age, comorbidities, and immunosuppressive regimen, because we could not demonstrate cardiac amyloid deposition in recipients from Val30Met donors by bone…

Spleen x-ray

Hydroxyurea Treatment Associated With Surgical Splenectomy in Children With SCD

Treatment with hydroxyurea might be associated with higher rates of surgical splenectomy in children with sickle cell disease (SCD) as well as younger age at intervention, according to a recent retrospective cross-sectional study published in the Journal of Surgical Research. To investigate the correlation between the widespread SCD therapy agent and surgical splenectomy among the…

Laparoscopic procedure

New 3-Step Laparoscopy Feasible and Effective in Intrahepatic Cholangiocarcinoma

A new 3-step laparoscopic approach improves the quality of liver resection and lymph node dissection, prolongs survival, and leads to better outcomes both during and after the operation in patients with advanced intrahepatic cholangiocarcinoma (ICC). This is according to a new study published in BMC Cancer.  Laparoscopic surgery for ICC can be challenging in patients…

surgery

Local and Radical Excision Have Similar Outcomes in Patients With Rectal GISTs

Although local surgical excision of a rectal gastrointestinal stromal tumor (GIST) may be associated with a higher incidence of positive margins than radical excision, there is no significant difference in overall survival between the 2 approaches, according to a recently published study in the World Journal of Surgery. Rectal GISTs are an uncommon finding associated with…

Hereditary Transthyretin (hATTR) Amyloidosis Surgical Management

Laparoscopic and Endoscopic Cooperative Surgery Safe and Feasible for Gastric GIST

Laparoscopic and endoscopic cooperative surgery is a safe and feasible procedure for the treatment of gastric gastrointestinal stromal tumors (GIST), according to a new study published in Endoscopy International Open. The authors said that the procedure is safe “despite several oncological concerns.” The oncological safety of the procedure for gastric GIST remains unclear despite the…

human lungs

Lung Transplant Allocation Among Patients With PAH Remains Inequitable

Researchers reported that patients with pulmonary arterial hypertension (PAH) remain least likely to receive a lung transplant and hence most likely to die while on the waiting list, despite recommendations made in 2015. The findings were published in the American Journal of Respiratory and Critical Care Medicine. PAH, characterized by elevated pulmonary vascular resistance, is potentially…

surgery

New Study Findings Could Guide Therapeutic Approaches for Duodenal GISTs

Novel insight into the epidemiological, clinical, and therapeutic data of gastrointestinal stromal tumors (GISTs) of the duodenum may lead to unified recommendations on their management and that of other primary duodenal malignant tumors (PDMT), according to a study recently published in the Journal of Gastrointestinal Oncology.  “In this retrospective study, we sought to analyze and evaluate…

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