Researchers reported that the use of musculoskeletal ultrasound during routine joint evaluations has a significant impact on how physicians formulate their physical therapy plans for patients with hemophilia-associated arthropathy. Their study is published in BMC Musculoskeletal Disorders. Hemophilia causes bleeding into the joints, which is a major source of morbidity. The extent of hemophilic arthropathy…
Researchers presented the case study of a patient who had duodenal edema secondary to previously undiagnosed hereditary angioedema in Internal Medicine. The 64-year-old woman presented with recurrent severe epigastric pain. She did not have any other medical complaints. A computed tomography scan revealed a thickened duodenal wall with ascites; an esophagogastroduodenoscopy showed mucosal and submucosal…
A novel contrast imaging method could effectively assess lymphatic involvement in patients with medullary thyroid carcinoma (MTC) and other thyroid neoplasms, according to a study recently published in Frontiers in Bioengineering and Biotechnology. “Microbubble contrast agent SonoVue is a valuable imaging contrast medium for thorough preoperative lymphatic mapping in patients with thyroid carcinoma, including the…
Researchers reported that the clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy may play a vital role in the early diagnosis of primary central nervous system lymphoma (PCNSL), according to a study published in Heliyon. PCNSL, otherwise known as diffuse large B-cell lymphoma (DLBCL) confined to the central nervous system, tends to…
A new study has determined that perfusion images acquired before and during vasodilation could distinguish between patients with pulmonary arterial hypertension (PAH) and controls without the disease. The study, published in Respiratory Research, revealed significant differences in the heterogeneity associated with vertical gradients in perfusion. “Here, we used positron-emission tomography and high-resolution computer tomography (PET-CT)…
Diffusion tensor imaging (DTI) could yield useful information in patients with Pompe disease (PD), according to a study recently published in the Journal of Neurology. “This study indicates that DTI holds promise and deserves further study as a potential parameter to monitor the effect of emerging treatments targeting the brain,” the authors wrote. The cross-sectional study…
The myelin water fraction and magnetization transfer ratio are useful markers of remyelination, according to a new study published in Brain Pathology. Moreover, measurements derived from diffusion tensor imaging may help measure myelin in the brains of patients with multiple sclerosis (MS). In addition, the researchers identified extensive astrogliosis in all lesions, even after remyelination, suggesting…
The use of positron emission tomography/computed tomography (PET/CT) for the diagnosis and management of medullary thyroid carcinoma (MTC) does not appear to be generalized in Spain, according to a recently published study in the Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging). Evidence shows that fluorodopa (F-DOPA)…
Hereditary transthyretin (hATTR) amyloidosis is a rare, multisystemic, progressive disease characterized by the accumulation of abnormal transthyretin protein (TTR) in various tissues and organs. It is an autosomal dominant disease that is endemic to certain geographical regions. Affected individuals inherit mutations to the TTR gene which lead to decreased folding stability of the TTR homotetramer,…
Researchers reported that patients with sickle cell disease (SCD) are particularly vulnerable to painful adverse events when given Definity, an ultrasound-enhancing agent, at high doses, according to a study published in the Journal of the American Society of Echocardiography. Modern uses of echocardiography typically incorporate ultrasound-enhancing agents to improve diagnostic accuracy and radiologist confidence in…
