Oncologists

Ectopic Cushing’s Syndrome May Cause Poorer Prognosis for Patients With MTC

Patients with advanced medullary thyroid carcinoma (MTC) who develop ectopic Cushing’s syndrome (ECS) may have a poorer prognosis than patients with MTC who do not develop ECS, according to a multicenter case series published in Clinical Endocrinology. The results found that patients with MTC with ECS had a shorter median overall survival (OS) time of…

Insights on Clinically Managing Ct-Negative Medullary Thyroid Carcinoma

Researchers recently revised the clinicopathological features of calcitonin (Ct)-negative medullary thyroid carcinoma (MTC) cases to share strategies for improving their clinical management since these cases are extremely rare and difficult to diagnose. “The diagnosis of Ct-negative MTC patients should be based mainly on imaging methods and clinical judgements,” Jingzhu et al said in a study…

Obese Populations May Be at Higher Risk for Gastrointestinal Stromal Tumors

Recent studies indicated that individuals who are morbidly obese demonstrated higher incidences of gastrointestinal stromal tumors (GISTs) than the general population, according to a study published in Medicina. Upon further investigation among individuals with obesity who underwent laparoscopic sleeve gastrectomies (LSGs), the incidence rate of GISTs was 0.31%. These GISTs were proven to be low-risk…

thyroid ultrasound

Reflecting on a 5-Year Journey to My MTC Diagnosis

Editor’s Note: In this Q&A, Patient Perspectives columnist Christine Pudel, RN, answers questions from her editor. A 30-year-old wife, mother to a son, and a registered nurse, Christine was diagnosed with medullary thyroid cancer (MTC) in 2016 and has undergone 2 surgeries, as well as radiation therapy. Her columns uniquely capture a life with MTC…

New Predictive Model Could Help Differentiate GISTs From Leiomyomas

Researchers in Korea have identified several factors that could differentiate between gastrointestinal stromal tumors (GISTs) and leiomyomas of the stomach.   Age, sex, homogeneity, location of the tumor, and the presence of anechoic spaces, dimpling, or ulcers on an endoscopic ultrasonography are factors that can facilitate the difference between the 2 diseases. This is according…

Laparoscopic Surgery May Be Advantageous for GIST Treatment

Surgical resection is a treatment for individuals with gastrointestinal stromal tumors (GISTs), however, questions have arisen about the highest efficacy among 2 surgical approaches: laparoscopic vs conventional open surgery. While both surgical types resulted in statistically similar rates of long-term patient outcomes such as overall and progression-free survival, laparoscopic surgeries demonstrated more statistically favorable short-term…

Genotype Analysis Can Help Predict Gastrointestinal Stromal Tumor Prognosis

A patient’s genotype is significantly associated with the risk of gastrointestinal stromal tumor (GIST) recurrence, according to a new study published in the Annals of Gastroenterological Surgery. Analyzing a patient’s genotype can therefore help predict disease prognosis and the best treatment approach.  The role of genotypes in the prognosis of GISTs has been controversial. Here,…

Patients With MTC Who Are Married May Have Better Prognosis

Patients with medullary thyroid carcinoma (MTC) who are married may have a better prognosis than patients who are unmarried, according to a new study published in Cancer Medicine. Researchers found that married patients had statistically higher overall survival (OS; P =.00071) and cancer-specific survival (CSS; P =.013) rates compared to their unmarried counterparts, based on…

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