neuropsychologists

Numeric Rating Scale Could Assess NMOSD Spasticity

Self-reported scores on the Numeric Rating Scale (NRS) from patients with neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) were correlated with physicians’ scores on the Modified Ashworth Scale (MAS) (r =.934; P <.001), as published in Multiple Sclerosis and Related Disorders. “Patients’ self-reported NRS score had a good correlation with clinician-evaluated MAS score…

Kappa Opioid Receptor Agonists Show Promise as MS Remyelinating Therapy

Researchers found that ethoxymethyl ether salvinorin B (EOM SalB), a salvinorin A analog, is effective in 2 different preclinical models of multiple sclerosis (MS), as published in Frontiers in Neurology. This finding supports kappa opioid receptor agonists as being a promising therapeutic target for demyelinating diseases. Salvinorin A is the main active psychotropic found in…

New Algorithm Could Predict MS Up to 5 Years Before Diagnosis

Researchers presented a new method of embedding electronic health records onto a biomedical knowledge graph to obtain high-dimensional health status profiles that can be used to identify people at risk of developing a chronic disease such as multiple sclerosis (MS), as published in the Journal of the American Medical Informatics Association. Using their new method,…

Disease-Modifying Therapies Could Help Protect Patients With MS From COVID-19

Patients with multiple sclerosis (MS) treated with interferon beta-1a (IFN) demonstrated significantly increased humoral responses to the Pfizer mRNA vaccine for COVID-19, according to new study results published in Multiple Sclerosis and Related Disorders. In contrast, patients with MS taking cladribine (CLAD), fingolimod (FTY), and ocrelizumab (OCRE) showed a weakened humoral response. Patients on CLAD,…

Epilepsia Partialis Continua May Represent a Relapse Phenotype in MS

Researchers suggest that epilepsia partialis continua (EPC) in relapsing-remitting multiple sclerosis (RRMS) may represent a distinct relapse phenotype, as published in Clinical Neurology & Neurosurgery. The case report was of a 35-year-old woman who presented with continuous left-hand jerking, which was compatible with EPC. Her past medical history revealed a diagnosis of RRMS and 2…

Visual Evoked Potential Recommended for Diagnosing MS in Pediatrics

Optic neuritis is a common first manifestation of multiple sclerosis (MS) in children, as published in the European Journal of Paediatric Neurology. The new study analyzed a Serbian population of 52 patients with the disease aged 7 to 17 years. “The present study is the largest series of pediatric multiple sclerosis in [the] Western Balkan…

Patients With MS May Develop Sarcopenia

Twenty percent of patients with multiple sclerosis (MS) had sarcopenia, according to a recent study published in Multiple Sclerosis and Related Disorders. The authors found that 17.64% of female patients and 21.21% of male patients had regional sarcopenia based on the values of sonographic thigh adjustment ratio (STAR), handgrip strength (HGS), and gait speed. However,…

doctor and patient

Recent MS Diagnosis Can Impact Initial Disease-Modifying Therapy Decisions

A recent diagnosis of multiple sclerosis (MS) leads to strong emotions including despair and hopelessness, according to a new study published in the journal Multiple Sclerosis and Related Disorders. These emotions can have an impact on the initial disease-modifying therapy decision. “Health care professionals need to understand the lived experience of patients making [disease modifying…

Imaging Criteria Shows High Accuracy in Differentiating NMOSD

Researchers compared the diagnostic performance of imaging criteria that differentiated aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD) and multiple sclerosis (MS) and discovered that it had high applicability at the earliest disease stages and is thus useful in clinical practice, as published in the European Journal of Radiology. Differentiating MS from AQP4+NMOSD early can help…

Next post in NMOSD News Briefs