Diagnosis & Disease Information

DMD history

A Study Will Address Muscle Strengthening Techniques for DMD

An upcoming study will evaluate the effects of trunk-oriented exercises compared to whole-body vibration as therapeutic options for patients with Duchenne muscular dystrophy (DMD). Researchers will soon initiate the recruiting process for this interventional study. The clinical trial will include approximately 30 participants previously diagnosed with DMD with randomized allocation and parallel assignment. Read more…

NMOSD

Study Reveals Factors Associated With NMOSD Misdiagnosis

Factors such as a delay in performing a magnetic resonance imaging (MRI) study, the presence of nonneurological symptoms, and a negative aquaporin 4 (AQP4) IgG test could contribute to a late neuromyelitis optica spectrum disorder (NMOSD) diagnosis detrimental to the health of the patient, according to a recently published study in Multiple Sclerosis and Related Disorders.…

MS brain

The Brains of Patients With MS and NMOSD Are Damaged in Different Ways

There are distinct patterns of structural damage and reorganization in the brains of patients with multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), found a new study published in the journal Multiple Sclerosis and Related Disorders. According to the authors of the study, these findings could help differentiate between the 2 diseases.  To explore…

Clinical Trial

EXPLORE44 Clinical Trial to Investigate AOC 1044 for DMD Now Recruiting

A new phase 1/2 clinical trial, EXPLORE44™ (NCT05670730), to investigate the use of AOC 1044 in healthy adult volunteers and patients with Duchenne muscular dystrophy (DMD) is now recruiting participants at a study location in San Antonio, Texas. The trial, sponsored by Avidity Biosciences Inc, will enroll patients during 2 different parts of the trial.…

Cardiomyopathy

Hereditary ATTR-CM Has a Poorer Prognosis Than the Wild-Type Form

Around one-fifth of elderly patients with transthyretin amyloidosis cardiomyopathy (ATTR-CM) have a pathogenic TTR variant, according to a study published in the European Journal of Heart Failure. ATTR-CM has gained increasing recognition in recent years, aided by advances in imaging studies, such as cardiac magnetic resonance and scintigraphy with bone tracers. This has coincided with…

Next post in hATTR News Briefs