MS News Briefs

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Teriflunomide Use Increasing in Patients With MS, Particularly Among Some Subgroups

A new study has found a significant and progressive increase in the use of teriflunomide in patients with multiple sclerosis (MS), particularly among treatment-naïve patients and young women. The study, published in the Journal of the Neurological Sciences, also found that age and disability levels were factors affecting the response to the treatment. “Since teriflunomide…

brain illustration

Cognitive Performance Predicts Self-Management in Patients With MS

Cognitive performance may predict self-management in patients with multiple sclerosis (MS), a study published in Multiple Sclerosis and Related Disorders suggests. Patients with poor self-management can develop several complications in the long run. The definition of self-management varies greatly. Generally speaking, it entails a patient who actively participates in the approach to managing their MS. The…

MRI imaging

Researchers Recommend Adding 3D FLAIR Sequences to MRI Protocol for MS

The use of 3D fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) sequencing detects significantly more multiple sclerosis (MS) brain lesions than 2D FLAIR sequencing, according to a study published in the Egyptian Journal of Radiology and Nuclear Medicine. The study also found that using maximum intensity projection (MIP) on the 3D FLAIR images enabled…

Human brain scan

Cognitive Impairment Correlates With Decreased Thalamic Volume in MS

Cognitive impairment correlated strongly with reduced thalamic volume and temporal lobe cortical thickness in patients with pediatric-onset multiple sclerosis (MS), according to findings published in the Egyptian Journal of Neurology, Psychiatry and Neurosurgery. Researchers analyzed the level of cognitive impairment as it related to brain volumetric measurements of 50 patients with pediatric-onset MS ranging from…

cannabis

Nabiximols Benefits Spasticity-Related Symptoms in MS

Nabiximols therapy reduced baseline spasticity symptoms in patients with multiple sclerosis (MS), a new study published in the European Journal of Neurology found. One-third of the studied patients maintained the treatment at 18 months. “This study aimed to assess the relationship between changes in spasticity severity (measured on the 0-10 [numerical rating scale] and the…

Central nervous system

Researchers Recommend Strategy for Managing MS With CNS Tumors

Disease-modifying therapies (DMTs) for patients with multiple sclerosis (MS) is desirable in patients with highly active and aggressive MS and concurrent central nervous system (CNS) tumors, a new study published in Neurological Sciences suggests. The clinical management of patients with simultaneous MS and CNS tumors is challenging due to several possible treatment limitations plus the intrinsic…

DMT

Discontinuing DMTs Leads to Disease Progression in MS Study

Discontinuation of disease-modifying treatment (DMT) leads to a progression of multiple sclerosis (MS) and a worsening in Expanded Disability Status Scale (EDSS) scores, according to a study published in Multiple Sclerosis and Related Disorders. Patients with relapsing-remitting MS were followed for 5 years during the study and DMT adherence and outcomes were monitored. Over the…

covid vaccine vials

B-cell Count Only Factor Associated With Response to COVID-19 Vaccine in MS

B-cell count is the only factor associated with serological response to tozinameran in patients with multiple sclerosis (MS), a new study published in the journal JAMA Network found. The optimum cutoff for a serological response is a B-cell count of at least 40/μL. Therefore, MS patients treated with rituximab should receive the tozinameran vaccine as…

Human brain with highlighted corpus callosum

Reduced Interhemispheric Connectivity May Contribute to Impairment in MS

Researchers discovered that preserving surface-based homologous interhemispheric connectivity (sHIC) in the cortex of the brain can help prevent physical and cognitive decline in multiple sclerosis (MS). The study findings were reported in Springer Nature.  The corpus callosum is particularly vulnerable to damage in MS due to its role as the primary interhemispheric tract of the…

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