IPF News Briefs

Patients With IPF and GERD Showed Higher Risk for Poor Outcomes

There is an association between idiopathic pulmonary fibrosis (IPF) and gastroesophageal reflux disease (GERD), according to results published in Chest. The study is being presented virtually at the Chest 2021 Annual Meeting on Oct. 17-20, 2021. The association between IPF and GERD was already known possibly due to chronic micro-aspiration leading to lung parenchyma remodeling.…

IPF exercise

Dedicated ILD Clinic Care Improves the Monitoring of Patients With IPF

A dedicated interstitial lung disease (ILD) clinic improves the care provided to patients with idiopathic pulmonary fibrosis (IPF), according to a recent study conducted by Gross et al. Improvements were observed even in clinics located in small healthcare systems, regardless of their association with a tertiary care center. The results of the study will be…

IPF exercise

Study Shows Body Mass Plays a Major Prognostic Role in IPF

A team of researchers discovered that weight plays a factor in determining clinical outcomes for patients with interstitial pulmonary fibrosis (IPF), according to a study published in Respiration.  In clinical settings, the body mass index (BMI) and body weight of patients with IPF are routinely measured. Weight loss is commonly experienced by IPF patients, which…

blood test for analysis

Matrix-Metalloproteinase-7: A Predictor of IPF Disease Progression

Findings from a meta-analysis demonstrated greater baseline blood matrix-metalloproteinase-7 (MMP-7) concentrations in patients with untreated idiopathic pulmonary fibrosis (IPF), according to a study published in the European Respiratory Journal. There was a 27% greater risk of disease progression and a 23% increased risk of mortality in patients, and these findings were independent of age, gender,…

idiopathic pulmonary fibrosis, lung scan

Cigarette Smoking Significantly Increases Risk of IPF

A team of Korean researchers discovered that cigarette smoking significantly increases the risk of developing idiopathic pulmonary fibrosis (IPF), according to a study published in Thorax. The association between smoking and IPF was clear enough for a dose-response relationship to be observed.  Medical researchers have long tried to establish the exact pathophysiology of IPF. A…

Idiopathic Pulmonary Fibrosis Treatment

Acute Exacerbations Have Different Outcomes in IPF and Non-IPF Patients

Patients with idiopathic pulmonary fibrosis (IPF) who develop acute exacerbations have a higher mortality rate than patients with other interstitial lung diseases (ILDs) who experience similar respiratory deterioration (43% vs 19%), according to a new study published in the journal Diagnostics. This conclusion is from a retrospective study that engaged 158 ILD patients (IPF, 38%,…

idioathic pulmonary fibrosis symptoms

New Findings May Explain How Obstructive Sleep Apnea Worsens IPF

Intermittent hypoxia worsens pulmonary fibrosis induced by bleomycin (BLM) in a mouse model, according to a new study by Chinese researchers published in International Immunopharmacology. This could be via reactive oxygen species (ROS)- and hypoxia-inducible factor1α (HIF-1α)-related oxidative stress and inflammation. These findings propose a possible mechanism of the worsening effect of episodes of obstructive…

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