The frequency of bleeding episodes stayed the same or decreased in most patients with hemophilia during the first coronavirus disease 2019 (COVID-19) lockdown, according to a new study published in Haemophilia. Positive results were also observed in these patients in terms of medication adherence and mental health. 

The lockdown had a detrimental effect on lifestyle behaviors, on the other hand, with an increase in screen time, a decrease in physical activity, and weight gain, the study reported.

The aim of the study led by Mathieu Boulin, PharmD, PhD, of University Hospital, Dijon in France was to explore the effect of the first COVID-19 lockdown on patients with hemophilia in terms of symptoms, management, medication adherence, mental health, and lifestyle.


Continue Reading

Read more about hemophilia patient education

The team contacted 284 patients with hemophilia A or B to participate in a prospective cross-sectional phone survey using a 2-part questionnaire. Of these patients, 239 participated in the survey, of which 183 were adults and 56 were children.

The results showed that the frequency of bleeding episodes remained unchanged or decreased in 81% of children and 78% of adults with hemophilia during the lockdown.

Among adults, medication adherence was 82%, and among children, it was 98.2%. Overall, the majority of adults (67%) and children (71%) “felt as good as before lockdown.” 

The 3 main lifestyle behavior changes in all patients were an increase in screen time in 49% of adults and 57% of children, a decrease in physical activity for 43% of adults and 48% of children, and weight gain in 32% of adults and 27% of children.

“Encouraging results were observed in terms of hemophilia symptoms, medication adherence, and mental health,” the researchers wrote. “Conversely, a negative impact was observed on lifestyle behaviors in a cohort of French hemophilia patients during the 1st lockdown.”

Reference

Volot F, Soudry-Faure A, Callegarin A, et al. Impact of first COVID-19 lockdown on paediatric and adult haemophilia patients treated in a French Haemophilia Comprehensive Care Centre. Haemophilia. Published online March 3, 2022. doi:10.1111/hae.14526