Endoscopic ultrasonography (EUS)-guided fine needle biopsy was useful for the diagnosis of a pancreatic gastrointestinal stromal tumor (GIST), as described in a case report published in the Journal of Gastroenterology and Hepatology. The patient had an 11-mm hypervascularized, neoplastic lesion on the pancreatic head identified using contrast-enhanced computed tomography (CT). The lesion was observed to…
Researchers from China developed a new combined radiomic model that can distinguish gastric gastrointestinal stromal tumors (GISTs) from leiomyomas and schwannomas. Their new model could assist endoscopic ultrasonography experts in diagnosing subepithelial lesions in a noninvasive manner, especially those that are smaller than 20 mm in diameter, the researchers said. Read more about the diagnosis of…
A modified cap-assisted endoscopic mucosal resection (mEMR-C) technique to treat intraluminal gastric gastrointestinal stromal tumor (GIST) measuring 20 mm or less leads to shorter operation times and lower costs compared to endoscopic submucosal dissection. This is according to a new study published in the journal Clinical and Translational Gastroenterology. Read more about GIST treatment To compare the outcomes…
Tumor invasion of the plasma membrane surface could influence the prognosis of gastrointestinal stromal tumor (GIST), according to a study recently published in the World Journal of Surgical Oncology. “Our results suggest that tumor growth patterns are independent predictors of progression-free survival, and that the exogenous type is associated with a significantly worse prognosis than the…
There are clinical improvements in the outcomes of imatinib treatment in patients with gastrointestinal stromal tumors (GIST) since the first randomized studies of the treatment 20 years ago. This is according to a new study by Dutch researchers published in the journal Targeted Oncology. “These results represent outcomes in real-world clinical practice and can serve…
Combined laparoendoscopic surgery can be used successfully to resect gastrointestinal stromal tumors (GISTs) located at the gastroesophageal junction according to a case study published in the International Journal of Surgery Case Reports. During the case, surgical resection of the GIST was achieved through the cooperative use of laparoscopy and upper gastrointestinal endoscopy. Due to the…
Adjusting treatment schemes for gastrointestinal stromal tumors (GIST) based on genetic variants could greatly benefit these patients, according to a study recently published in Drug Design, Development and Therapy. “Currently, there is a trend to use individualized dosing to address the wide variation in pharmacokinetics between patients, and then to avoid efficacy being compromised by…
Depression of ETS variant 1 (ETV1) levels inhibited the progression of gastrointestinal stromal tumor (GIST) cells, according to a study published in the Journal of Clinical Biochemistry and Nutrition. The study validated a previous observation that increased ETV1 expression was linked to GIST pathogenesis. Knockdown of ETV1 expression halted the progression of GIST cells induced…
According to a recent World Journal of Surgical Oncology study, new diagnostic techniques such as angiography, enteroscopy, and capsule endoscopy should be used for suspicious lesions for small bowel gastrointestinal stromal tumors (GISTs), which often require a long time to be diagnosed. The study also highlighted that surgical resection is often associated with exceptional postoperative recovery and…
A new study that aims to compare the safety and efficacy of apatinib mesylate to standard second-line tyrosine kinase inhibitor therapy in patients with advanced gastrointestinal stromal tumors (GIST) is now recruiting participants in China. The randomized, open-label, controlled, single-center clinical study aims to recruit 258 patients with GIST, 18 years of age and over,…
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