A case report of a mother and her children with familial medullary thyroid carcinoma (MTC) was presented as an ePoster at the 2023 International Meeting of Pediatric Endocrinology (IMPE 2023). A 32-year-old mother was diagnosed with metastatic MTC after progressive weakness of her extremities, weight loss, and dysarthria. She was found to have a TGC-TGG…
For patients with diffuse large B-cell lymphoma who fail first-line therapy, a few second-line options remain.
A prognostic index, called the geriatric prognostic index (GPI), was developed for older patients with diffuse large B-cell lymphoma (DLBCL) who are candidates for treatment with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). The new GPI outperformed the most widely used clinical prediction models, including the international prognostic index (IPI), the revised IPI (R-IPI), and…
FF-10502-01 is well tolerated with manageable side effects, in patients with solid tumors, including cholangiocarcinoma, according to a new study published in the journal Cancer. The treatment also had limited hematologic toxicity. The study also found that in patients with cholangiocarcinoma who were heavily pretreated with gemcitabine, FF-10502-01 led to durable partial responses and disease…
Serum extracellular vesicles (EVs) appear to contain proteins that could serve as potential biomarkers and aid in the early diagnosis and prognosis of cholangiocarcinoma (CCA), according to a recently published study in the Journal of Hepatology. Although the incidence of CCA has risen significantly in recent decades, most patients have a poor prognosis, mainly because many…
The management, epidemiology, and clinical outcomes of cholangiocarcinoma in Africa were systematically reviewed and published in BMC Gastroenterology. There were only 11 studies from 4 African countries, which is not representative of the whole continent. “Our current review provides some foundational published work needed to guide future studies and support proposed research,” first author Akwi…
A study submitted to Research Square has revealed that even though uveal metastases (UM) originating from thyroid neoplasms are relatively rare, they might still threaten the eyesight of every patient with thyroid cancer. The study suggested that physicians should be alert and consider the possibility of UM if patients report ocular symptoms, a neck mass, or…
Medullary thyroid carcinoma (MTC) could coexist with ectopic bone formation (EBF) inside the thyroid gland, according to a study recently published in the journal European Review for Medical and Pharmacological Sciences. “Based on our view, we recommend that all patients with histopathological findings of EBF or EMH in thyroid biopsy or thyroidectomy specimens should be…
I was faced with a very rare type of cancer when I was diagnosed with medullary thyroid cancer (MTC).
A team of researchers from China developed a nomogram to assess the risk of venous thromboembolism in patients undergoing surgery for distal cholangiocarcinoma. They published their research in the Asian Journal of Surgery. The rate of venous thromboembolism is high among patients undergoing distal cholangiocarcinoma surgery and is associated with adverse outcomes. Read more about…
