Junction: Neurology

muscle cell tissue

Muscle Shear-Wave Elastography Useful for Monitoring DMD Progression

Ibrahim and Ayşe explored the application of muscle shear-wave elastography (SWE) as an adjunct clinical tool in monitoring pediatric musculoskeletal disorders such as Duchenne muscular dystrophy (DMD). Their study is part of a book published under the working title of Elastography – Applications in Clinical Medicine. Magnetic resonance imaging elastography and ultrasound elastography are technological…

Numeric Rating Scale Could Assess NMOSD Spasticity

Self-reported scores on the Numeric Rating Scale (NRS) from patients with neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) were correlated with physicians’ scores on the Modified Ashworth Scale (MAS) (r =.934; P <.001), as published in Multiple Sclerosis and Related Disorders. “Patients’ self-reported NRS score had a good correlation with clinician-evaluated MAS score…

person in wheelchair

Perceived Nusinersen Efficacy May Be Important to Adults With Severe SMA

A new French retrospective study published in Revue Neurologique reveals the importance of using both subjective and objective methods to assess treatment efficacy in adults with spinal muscular atrophy (SMA) who use a wheelchair. The research team evaluated the efficacy of nusinersen, an intrathecally administered drug, by means of the conventional 32-item Motor Function Measurement…

High Serum IgG3 Antibodies as a Potential Blood Biomarker for MS

Recent studies show that immunoglobulin G3 (IgG3) heavy chain polymorphisms strongly associate with susceptibility to developing multiple sclerosis (MS). A study conducted by Kennedy et al, published in the Journal of Neuroimmune Pharmacology, concurs, reporting that higher levels of total immunoglobulin (IgG) and IgG3 occur in MS patients but not in patients with other neurological…

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