What We Can Learn From a Case Study of Myasthenia Gravis Occurring With COVID-19
During the height of the COVID-19 pandemic, physicians reported treating new cases of myasthenia gravis post-infection.
Junction: Myasthenia Gravis
Strategies for Managing Fatigue in Myasthenia Gravis
I think it’s important for chronic illness patients to find ways to mentally and physically separate from the fatigue and discomfort they are experiencing.
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People With Rare Diseases Report Facing Stigma, Poor Quality of Life
People with rare diseases who live in the United States have a poor health-related quality of life and experience significant stigma, according to a study published in the Orphanet Journal of Rare Diseases. A rare disease in the United States can be defined as any disease in which the prevalence is less than 200,000 cases.…
Phase 3 Myasthenia Gravis Trials Yield Positive Results for 2 Potential Therapies
Positive results from 2 phase 3 clinical trials of potential generalized myasthenia gravis (gMG) therapies were recently presented as posters at the 14th Myasthenia Gravis Foundation of America (MGFA) International Conference on Myasthenia and Related Disorders. The 2 therapies, zilucoplan and rozanolixizumab, were both associated with improvements in Myasthenia Gravis Activities of Daily Living (MG-ADL)…
Fatigue and Muscle Weakness in People With MG Are Not the Same
I imagine any myasthenia gravis (MG) patient would describe fatigue as a constant or intermittent part of their disease, yet fatigue is often described in relation to muscle weakness in terms of MG symptoms. Fatigue is not included in the Myasthenia Gravis Activities of Daily Living, (MG-ADLs), but since it is such a common symptom…
Quality of Life Questionnaire Recommended When Treating Myasthenia Gravis
Researchers studying the accuracy of quality of life (QoL) scales in patients with myasthenia gravis recommended their use in clinical practice because some symptoms of the disease can be difficult to examine, according to a study published in the Journal of Clinical Medicine. Myasthenia gravis is an autoimmune disease in which the neuromuscular junction is…
Case Studies Suggest Etiopathogenetic Link Between NMOSD and Myasthenia Gravis
Two cases of coexisting neuromyelitis optica spectrum disorder (NMOSD) and myasthenia gravis (MG) suggest a possible etiopathogenetic link between the diseases, reports a study published in Multiple Sclerosis and Related Disorders. Using next-generation sequencing (NGS), 2 mutant human leukocyte antigen (HLA) alleles were found in common between the 2 patients—HLA-DQA1*05:01:01 and HLA-DPB1*04:02:01. “To summarize, although…
Benefits of COVID-19 Vaccine Outweigh the Risks in MG, Study Suggests
Researchers assessing the safety of vaccines for patients with myasthenia gravis (MG) found that some of them, such as the anti-SARS-CoV-2, may cause MG exacerbations, but evidence points overwhelmingly in favor that they are still recommended for these patients, as published in the Journal of Neurology. MG, a chronic autoimmune disease affecting the neuromuscular junction,…
Lymphoplasma Exchange Effective in Some Myasthenia Gravis Cases
Lymphoplasma exchange is an effective treatment for patients with myasthenia gravis who are in a state of exacerbation or in preparation for a thymectomy, according to a new retrospective study performed in a Chinese center. According to the authors of the study, published in Frontiers in Immunology, the early use of lymphoplasma exchange on early-onset…
Variability of Myasthenia Gravis Symptoms Makes Diagnosing, Treating the Disease Difficult
Myasthenia gravis (MG) is a complicated disease that takes an average of 2 years and 3 to 4 physicians to diagnose, expert Henry Kaminski, MD, said.
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