Gastrointestinal Stromal Tumor History
The term gastrointestinal stromal tumor (GIST) was coined in 1983 by Mazur and Clark when they studied the histological origins of these tumors, found in the interstitial cells of Cajal.1 The interstitial cells of Cajal are specialized pacemaker nerve cells of the sympathetic nervous system which drive the rhythmic, peristaltic activity of the intestinal smooth…