Latest News
Acute Mast Cell Leukemia Preceded by Germ Cell Tumor: A Case Report
Novel Genetic Profile Identified in Case of Systemic Mastocytosis
People With Rare Diseases Report Facing Stigma, Poor Quality of Life
Patient With SM Undergoes Anesthesia Without Complications
Bezuclastinib for Advanced SM: Phase 2 Data Coming Soon
Mast Cell Metabolites Link to Systemic Mastocytosis Symptoms
FcεRI Expression in Mast Cells Regulated By External Stimuli
Basic Morphology, Immunohistochemical Panel Can Be Used to Diagnose SM
A Rare Incidence of Systemic Mastocytosis With Pulmonary Involvement
SM Clinical Trials
Features & Insights
The Importance of a Multidisciplinary Approach When Treating Systemic Mastocytosis
Given the complexity of systemic mastocytosis, the disease is best managed in a multidisciplinary setting.
Mastocytosis (Urticaria Pigmentosa, Telangiectasia Macularis Eruptiva Perstans)
Many children and adults have few, if any, symptoms. When symptoms do occur, they are due to the diverse physiologic effects of secreted mast cell mediators, such as histamine, eicosanoids and cytokines.
Clonal and non-clonal mast cell activation disorders
Mast cell activation disorders are a heterogeneous group in which patients present with signs and symptoms of disease mediated by the synthesis and release of activation products such as reformed vasoactive amines, newly generated arachidonic acid derived mediators, and induced cytokines.
Patient Perspectives
The Journey to My Diagnosis With Systemic Mastocytosis
After countless colonoscopies and multiple steroid treatments, biopsies determined I had abnormally large counts of white blood cells.
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