Latest ALGS News
Latest Clinical Trials
- Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome (ASSERT)
- Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome (ASSERT-EXT)
- A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)
- Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome (ITCH)
- Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS) (ICONIC)
Congenital genetic diseases sometimes display characteristic clinical manifestations that direct physicians to conduct the necessary tests to arrive at a correct diagnosis. However, other genetic diseases may be more insidious and are diagnosed only later in life (if at all), which means the early window for the initiation of critical medical intervention is missed. When…
In the South African Journal of Child Health, Dempster and colleagues detail the case of a patient who was simultaneously diagnosed with 2 rare disorders: Alagille syndrome and von Willebrand disease. A 17-year-old female patient presented with hypochromic anemia and splenomegaly. She had been diagnosed with Alagille syndrome in infancy due to having characteristic features…
Although Alagille syndrome is a multisystem disease, occasionally it can affect one organ more prominently than others.
Oral manifestations of Alagille syndrome, such as the greenish discoloration of the teeth, can be psychologically distressing to patients.
When it comes to my son, who lives with Alagille syndrome (ALGS), it is challenging for me to discipline him.
Once my son was diagnosed with Alagille syndrome (ALGS), we realized that my daughter’s genetic test was likely to confirm the JAG mutation for the disease.
When you have a child with ALGS it can be hard to take time away to recharge and not feel an overwhelming amount of guilt.
After my son was diagnosed with Alagille syndrome (ALGS), we realized how quickly the medical expenses piled up.
Pediatric gastroenterologist Dr. Henry Lin describes growth, nutritional, and psychosocial considerations for clinicians managing patients with ALGS.
Dr. Henry Lin reviews common clinical presentations and management considerations for renal, skeletal, ocular, and vascular involvement in ALGS.
Pediatric gastroenterologist Henry Lin, MD, MBA, reviews how the liver and cardiac system are involved in Alagille syndrome.
Kristen Baugher knew shortly after giving birth to her daughter, Emmery, that something was wrong. Jaundiced and weak, the baby itched uncontrollably.