Is Scoliosis Surgery in Patients With SMA Evidence-Based?
Spinal muscular atrophy (SMA) is a disorder characterized by muscle atrophy and weakness. It is inherited in an autosomal recessive manner and is caused by mutations/deletions in the SMN1 gene, which ensures adequate levels of survival motor neuron proteins in the body. Patients with SMA tend to experience proximal muscle weakness, especially in the lower…