The Dangerous Implications of Paroxysmal Nocturnal Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is a condition that is poorly defined and difficult to diagnose. Characterized by episodic complement-mediated hemolysis, its classic presentation is the sudden, episodic, and night-time occurrence of hemoglobin in the urine. The most common symptom shared by patients with this disease is debilitating fatigue. According to the International Paroxysmal Nocturnal Hemoglobinuria…
