hATTR Insights

Human heart anatomy

Treating Cardiac ATTR: Current Strategies and Challenges

For many years, the treatment of cardiac hereditary transthyretin amyloidosis (hATTR) relied on liver transplantation to remove the source of aberrant transthyretin (TTR). However, several studies have shown that liver transplantation provided an incomplete cure. Hence, combined liver/heart transplantation has emerged as an alternative. In addition to obvious transplant-associated limitations, such as the dependence on…

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