CC Insights

The Challenges of Lymphadenectomy in Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma is classified according to its occurrence along the biliary tree. For patients with intrahepatic cholangiocarcinoma, surgical resection is the only curative option. However, even post-surgery, intrahepatic cholangiocarcinoma is still associated with a high recurrence rate and poor survival.  Lymph node metastasis is one of the most significant prognostic indicators post-surgery. However, detecting lymph node…

liver transplant

What’s Next in Cholangiocarcinoma Management

Cholangiocarcinoma (CCA) is a highly aggressive group of cancers that occur in the biliary tree and are classified according to their location: intrahepatic, perihilar, and distal. It is one of the most common primary hepatic malignancies, second to only hepatocellular carcinoma. It has a global annual incidence of 0.3 to 6 per 100,000 population and…

health test

The Role of MicroRNAs in the Pathogenesis, Diagnosis, and Treatment of Cholangiocarcinoma

Cholangiocarcinoma (CCA) is an aggressive form of biliary malignancy with a dismal 5-year postoperative survival rate. The incidence of CCA is increasing globally, accounting for approximately 2% of all cancer-related deaths. As such, there is an urgent need for diagnostic and prognostic biomarkers to aid in early disease detection and help guide treatment.  Recently, a…

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