We explore the importance of assessing the nutritional status of infants diagnosed with a chronic cholestatic liver disease.
We explore the role of next-generation sequencing in providing a genetic diagnosis for infants with a cholestatic disease, such as Alagille syndrome or AATD.
We look into the progress made in the 3D visualization of bile duct abnormalities in patients with Alagille syndrome.
We explore the role of 3D cultures in medicine today and discuss their role in helping us understand ALGS disease processes.
Cholestasis is a defining clinical feature of Alagille syndrome (ALGS), but it is not found exclusively in ALGS patients.
When conducting medical research into organ-specific diseases, scientists often have to either retrospectively or prospectively recruit patients with the relevant medical conditions. However, all modern clinical trials must be approved by an ethics board, and some trials are simply deemed too risky to be conducted on human subjects. In addition, any tests done on human…
We discuss a case study of a successful pregnancy in a woman with Alagille syndrome and the potential role of genetic counseling.
Therapies under investigation for Alagille syndrome would offer physicians the means to target defective areas in a more focused manner.
We explore the role of genomic sequencing in diagnosing Alagille syndrome and some of the dilemmas of genetic testing for this disease.