The Prevalence of Liver Disease in Patients With Alagille Syndrome
Liver disease is one of the most common manifestations of Alagille syndrome and contributes significantly to healthcare utilization.
Liver disease is one of the most common manifestations of Alagille syndrome and contributes significantly to healthcare utilization.
The belief driving drug repurposing is that the current drugs that we do have may yet possess therapeutic aspects we aren’t fully aware of.
Researchers present the case study of a patient who presented with multiple arterial stenoses and was later diagnosed with Alagille syndrome.
Liver transplantation is often urgently required in patients with Alagille syndrome and end-stage liver disease.
Patients who are diagnosed with Alagille syndrome early in life may develop hepatocellular carcinoma much later.
Liver organoids have been used to regenerate hepatocellular parenchyma and bile ducts, providing a convenient platform for research and clinical purposes.
Congenital genetic diseases sometimes display characteristic clinical manifestations that direct physicians to conduct the necessary tests to arrive at a correct diagnosis. However, other genetic diseases may be more insidious and are diagnosed only later in life (if at all), which means the early window for the initiation of critical medical intervention is missed. When…
In the South African Journal of Child Health, Dempster and colleagues detail the case of a patient who was simultaneously diagnosed with 2 rare disorders: Alagille syndrome and von Willebrand disease. A 17-year-old female patient presented with hypochromic anemia and splenomegaly. She had been diagnosed with Alagille syndrome in infancy due to having characteristic features…
Although Alagille syndrome is a multisystem disease, occasionally it can affect one organ more prominently than others.
Oral manifestations of Alagille syndrome, such as the greenish discoloration of the teeth, can be psychologically distressing to patients.