Current and Potential Therapeutic Possibilities in Alagille Syndrome
Therapies under investigation for Alagille syndrome would offer physicians the means to target defective areas in a more focused manner.
ALGS Insights
Genome Sequencing Increases Diagnostic Accuracy in Alagille Syndrome
We explore the role of genomic sequencing in diagnosing Alagille syndrome and some of the dilemmas of genetic testing for this disease.
The Risk of Hepatocellular Carcinoma in Patients With Alagille Syndrome
In rare cases of ALGS, patients also develop hepatocellular carcinoma (HCC), with only about 30 cases being reported in the literature.
Differential Diagnosis of Central Hepatic Regenerative Nodules in ALGS
Pediatric and adult ALGS patients may sporadically present benign hepatic nodules, also known as regenerative or regenerating nodules.
Targeting Intrahepatic Bile Duct Paucity in Alagille Syndrome
Researchers at the University of Pennsylvania highlight the improvements in disease modeling afforded by a molecular understanding of Alagille syndrome.
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