The Challenge and Importance of Detecting AATD in Patients With Asthma
It is challenging for physicians to diagnose AATD in a patient with an existing asthma diagnosis since so many symptoms overlap.
AATD Insights
Understanding the Disease Burden of AATD
Patients with alpha-1 antitrypsin deficiency, along with their caregivers, struggle with a significant and multifaceted disease burden.
The Practicality of At-Home Therapy for Treating AATD
Self-infusion is an option for patients with alpha-1 antitrypsin deficiency, meaning that the bulk of treatment can now take place at home.
The Challenges of Using Gene Therapy to Treat Respiratory Disease
Researchers are increasingly exploring the potential of gene therapy in treating respiratory diseases.
Clinicians Weigh in on When Augmentation Therapy Is Called for in AATD
Today, experts are increasingly recognizing the positive role that ordinary physicians can play in refining diagnostic and management guidelines.
AATD Insights, CAD Insights, DMD Insights, Insights, LAL-D Insights, LCFAOD Insights, MG Insights, MTC Insights, SCD Insights
The Far-Reaching Impact of Innovative Clinical Trial Designs in Rare Disease
We examine the lasting impact of innovative clinical trial designs for rare diseases on other clinical experiments.
The Manifestations of AATD: Beyond the Pulmonary Pathology
We explore the various pulmonary and extrapulmonary manifestations of AATD, and the role of AAT augmentation therapy in both sets of symptoms.
Precision Medicine Becoming Increasingly Important in Treating AATD
We discuss the increasingly prevalent role of precision medicine in treating genetic diseases such as alpha-1 antitrypsin deficiency (AATD).
Examining the Pathological Effects of AATD on the Liver
We explore the evidence on the pathological effects of AATD on the human liver, particularly in individuals with the Pi*ZZ mutation.
Addressing Protein Misfolding in AATD Could Lead to Improved Therapies
Protein misfolding and its consequences are a key mechanism in the pathophysiology of alpha-1 antitrypsin deficiency.
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