Insights

Insights, MTC Insights

The Role of CCK2R in Nuclear Imaging for Medullary Thyroid Carcinoma

By

Ryner Lai, MBBS

Publish Date January 21, 2022

We examine the role of the cholecystokinin-2 receptor (CCK2R) in MTC nuclear imaging, and discuss methods of targeting it more efficiently.

GIST Insights, Insights

The Benefits of Laparoscopic Surgery vs Open Surgery for GIST

By

Ryner Lai, MBBS

Publish Date January 20, 2022

We describe the numerous benefits that laparoscopic surgery confers to patients with GIST, compared to open surgery.

ALGS Insights, Insights

Assessing Infant Malnutrition Secondary to Chronic Cholestatic Liver Disease

By

Ryner Lai, MBBS

Publish Date January 20, 2022

We explore the importance of assessing the nutritional status of infants diagnosed with a chronic cholestatic liver disease.

CC Insights, Insights

The Crucial Role of Correct, Timely Diagnosis in the Management of CCA

By

Ryner Lai, MBBS

Publish Date January 19, 2022

We explore the importance of correct and timely diagnosis of cholangiocarcinoma (CCA), which can be divided into iCCA, pCCA, and dCCA.

HEM Insights, Insights

Barriers Remain in Gene Therapy for Hemophilia Despite Clinical Advancements

By

Juliana Campos, PhD

Publish Date January 19, 2022

An increasing number of studies support the use of gene therapy in patients with hemophilia. However, several factors restrict its wide application.

Insights, IPF Insights

How Telomere Dysfunction Drives Pathogenesis in IPF

By

Ryner Lai, MBBS

Publish Date January 18, 2022

We explore how telomere dysfunction potentially drives the pathogenesis of idiopathic pulmonary fibrosis, and what that could mean for future research.

Insights, MTC Insights

Exploring TKI-Induced Nephrotoxicity in Patients With Medullary Thyroid Carcinoma

By

Ryner Lai, MBBS

Publish Date January 14, 2022

We explore various issues related to nephrotoxicity induced by tyrosine kinase inhibitors in patients with medullary thyroid carcinoma.

DMD Insights, Insights

Genetic Correction Strategies and Their Cardiac Impact in Patients With DMD

By

Ryner Lai, MBBS

Publish Date January 14, 2022

We investigate the genetic correction strategies available for DMD patients today and assess their impact on the heart.

Insights, PAH Insights

Exploring the Cause and Effect of Endothelial Dysfunction in PAH

By

Ryner Lai, MBBS

Publish Date January 14, 2022

Endothelial dysfunction is a prominent feature of pulmonary arterial hypertension. We explore the cause and effects of it.

AATD Insights, ALGS Insights, Insights

The Role of Next-Generation Sequencing in Diagnosing Infants With Cholestasis

By

Ryner Lai, MBBS

Publish Date January 14, 2022

We explore the role of next-generation sequencing in providing a genetic diagnosis for infants with a cholestatic disease, such as Alagille syndrome or AATD.