History of Hereditary Angioedema
Hereditary angioedema (HAE), a genetic disorder inherited in an autosomal-dominant pattern, is characterized by severe swelling in the limbs, face, intestinal tract, and airways.1 In retrospective studies, researchers tracked down in church records from the 17th century what they believed to be the first documented cases of hereditary angioedema, describing “hereditary periodic edema” in a…