hATTR Features

Doppler echocardiogram

Recommendations for Multimodality Imaging in Patients With hATTR Affecting the Heart

Hereditary transthyretin (hATTR) amyloidosis is a rare, multisystemic, progressive disease characterized by the accumulation of abnormal transthyretin protein (TTR) in various tissues and organs. It is an autosomal dominant disease that is endemic to certain geographical regions. Affected individuals inherit mutations to the TTR gene which lead to decreased folding stability of the TTR homotetramer,…