The effectiveness and role of radiotherapy for patients with gastrointestinal stromal tumors (GISTs) may need to be reevaluated, according to findings that were recently published in Cancers. GISTs are believed to be resistant to radiotherapy and their use is primarily for palliative care. However, because patients with GISTs are expected to live longer compared with…
Automated monitoring of online patient forums may provide real-world data on adverse drug events (ADEs) and could be used to supplement pharmacovigilance, according to a study of patients with gastrointestinal stromal tumors. The research was published in Scientific Reports. Clinical trials are often relatively short in duration and are conducted in a small sample of…
Shorter operative time, a simpler operation, and faster postoperative recovery time are some of the advantages of hand-assisted laparoscopic surgery (HLS) compared with total laparoscopic surgery (TLS) for the surgical treatment of gastric gastrointestinal stromal tumors (GISTs), according to a retrospective analysis published in BMC Surgery. TLS has replaced open surgery for the treatment of…
Cardiovascular magnetic resonance imaging (CMR) may be useful in detecting clinically relevant changes in right ventricular (RV) volumes and function related to pulmonary arterial hypertension (PAH), according to a study published in Pulmonary Circulation. Targeted therapy has demonstrated a reduction in morbidity and mortality in patients with PAH. As RV dilatation may predict clinical worsening…
Inebilizumab-cdon (Uplizna®) may reduce attack risk and disability in patients with neuromyelitis optica spectrum disorder (NMOSD) who typically have poor treatment response, according to phase 3 pivotal trial data recently presented at the Consortium of Multiple Sclerosis Centers Annual Meeting. Most patients with NMOSD, a neuroinflammatory autoimmune disease, test positive for anti-aquaporin-4 (AQP4) antibodies, with…
A future definitive trial is not feasible to assess the acceptability of neuromuscular electrical stimulation of the quadriceps muscles in people with idiopathic pulmonary fibrosis.
In patients with fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis, adding pirfenidone to treatment may attenuate disease progression.
