Ryner Lai, MBBS

Ryner Lai, MBBS

Dr Ryner Lai (MBBS) is a medical graduate from Queen Mary, University of London. He is a medical writer who is passionate about the power of medical research to transform the lives of patients.

All articles by Ryner Lai, MBBS

Sebelipase Alfa Granted Breakthrough Therapy for Rare Autosomal Disorder

Combined Use of CT and MRI Improves Detection of Cholangiocarcinoma

Researchers have discovered that the use of magnetic resonance imaging (MRI) and computed tomography (CT) together in patients with cholangiocarcinoma (CCA) carries a high diagnostic value, according to a study published in the Journal of Oncology. The combination of imaging methods yields high sensitivity and specificity for CCA and can thus be highly valuable for…

malignant tumor

Gastrointestinal Bleeding Confirmed as an Indicator of Overall Survival in GIST

Gastrointestinal (GI) bleeding, one of the most common clinical manifestations of gastrointestinal stromal tumors (GISTs), worsens overall survival (OS) in GIST patients, compared to non-bleeding patients, according to a systematic literature review published in Technology in Cancer Research & Treatment. They also discovered the following 5 factors as significant in impacting the risk of GI…

LCFAOD diagnosis

The Role of Mitochondrial Dysfunction and Oxidative Imbalance in Fatty Acid Oxidation Disorders

Mitochondrial fatty acid β-oxidation disorders (FAODs) are a group of approximately 20 inherited diseases resulting from genetic mutations that codify enzymes or proteins involved in mitochondrial β-oxidation and fatty acid transport. FAODs have a combined incidence of about 1:9000 and are fairly common inborn errors of metabolism.  When glycogen is absent, FAO becomes a vital…


Potential Biomarker for Distal Cholangiocarcinoma Discovered

Researchers have discovered that serum thrombospondin-2 (THBS2) can combine with carbohydrate antigen (CA) 19-9 to serve as a potential biomarker combination for distal cholangiocarcinoma (dCCA) and pancreatic ductal adenocarcinoma (PDAC), according to a study published in Clinical and Transatlantic Oncology. The most important clinical implication of this study is that THBS2 can be used with CA…

sma surgery

Predicting the Effectiveness of Surgical Treatment in Cholangiocarcinoma

Researchers have discovered that surgical resection with negative margins increases long-term survival in cholangiocarcinoma (CCA )patients, according to a study published in The American Surgeon. They also discovered that the presenting size of the tumor and pathological stage play a significant role in predicting survival rates post-surgery, highlighting the importance of early diagnosis and surgical…

ms complications

The Role of Intrathecal Immunoglobulin M Synthesis In Predicting Aggressive MS

A hallmark of multiple sclerosis (MS) is intrathecal immunoglobulin (Ig) M synthesis (ITMS) due to the chronic activation of the immune system. Researchers discovered that ITMS is useful as a predictor of aggressive MS in patients with a clinically isolated syndrome (CIS), according to a study published in Neurology & Neuroinflammation. In addition, researchers also…

IPF therapies

The Role of CT Texture Analysis In Classifying Gastric Tumors

Researchers have discovered that quantitative computed tomography (CT) texture analysis is a promising and noninvasive method for the classification of gastric tumors and prediction of gastric adenocarcinoma differentiation, according to a study published in the Japanese Journal of Radiology.  Gastric tumors, such as gastrointestinal stromal tumors (GISTs), are routinely diagnosed using endoscopic biopsy, an invasive…

woman prepares an IV Drip

Home Infusion of Natalizumab Appears Promising for People With MS

A pilot randomized crossover study has found that there was no difference in the safety and efficacy between clinical and home infusions of natalizumab in patients with multiple sclerosis (MS), according to a study published in the Medical Journal of Australia. Natalizumab is an intravenous infusion commonly administered under physician supervision in patients with relapsing-remitting…

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