Ankle arthrodesis performed in patients with hemophilic ankle arthropathy may improve pain and functioning while keeping revision and complication rates low, according to a study published in Haemophilia. The authors conducted a literature review to investigate the mid- to long-term postoperative outcomes of ankle joint fusion in patients with hemophilia. They sought to understand the…
Patients with hereditary angioedema typically present with acute localized swelling at a particular area of their body.
Researchers will soon start recruiting for a clinical trial that will examine the use of fecal microbiota transplantation to offer symptomatic relief for diarrhea induced by nintedanib in patients with idiopathic pulmonary fibrosis (IPF). This interventional trial intends to enroll 114 participants, and double blinding will be applied. All participants must be adults diagnosed with…
Sickle cell disease is a chronic condition in which patients often experience comorbidities and associated pain.
Treatment compliance is key when it comes to treating primary carnitine deficiency, which is a lifelong illness.
A boy with alpha-1 antitrypsin deficiency (AATD) underwent a liver transplantation from a heterozygous donor, researchers reported in Pediatric Transplantation. The 9-year-old boy was diagnosed with AATD (ZZ phenotype) at 4 months of age. At that time, he presented with hepatomegaly and was treated with ursodeoxycholic acid and offered supportive care. At 7 years of…
A growing body of evidence suggests that omalizumab could be used to significantly alleviate symptoms associated with systemic mastocytosis.
There are more than 1000 plant species that may have therapeutic relevance in tackling neurodegenerative diseases such as Friedreich ataxia, spinal muscular atrophy, and multiple sclerosis, according to a study published in IBRO Neuroscience Reports. While significant pharmacological progress has been made for certain diseases (such as those involving the cardiopulmonary system), effective therapies tackling…
Despite improvements in our understanding of the pathophysiology of pulmonary arterial hypertension (PAH), it remains a disease of significant morbidity and mortality. PAH is characterized by dyspnea/fatigue, a common presentation among patients with heart failure. A diagnosis of PAH can only be made when other cardiac/pulmonary causes of increased pulmonary arterial pressure have been ruled…
Liver disease is one of the most common manifestations of Alagille syndrome and contributes significantly to healthcare utilization.
