Ryner Lai, MBBS

Ryner Lai, MBBS

Dr Ryner Lai (MBBS) is a medical graduate from Queen Mary, University of London. He is a medical writer who is passionate about the power of medical research to transform the lives of patients.

All articles by Ryner Lai, MBBS

fatigued woman

Fatigue in AAV May Meet Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

A sizeable portion of individuals with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) experience fatigue severe enough to meet the diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome, according to a study published in The Lancet Regional Health — Americas. The authors of this study sought to assess fatigue in patients with AAV to see if it…

Chest ultrasound

TAPSE/PASP Ratio May Predict Prognosis in Lung Transplant Candidates With PAH

A low ratio of tricuspid annular plane systolic excursion (TAPSE) to pulmonary arterial systolic pressure (PASP) is predictive of poorer prognosis in patients with pulmonary arterial hypertension (PAH) undergoing evaluations for lung transplantation suitability, according to a study published in Scientific Reports. The authors of this study conducted a retrospective investigation into the predictive value…

immune system: white blood cells, antibodies, complement system, lymphatic system.

New Selective Alternative Complement Pathway Inhibitor May Help Treat PNH

SAR443809, a selective inhibitor of the alternative complement pathway, has demonstrated strong potential for the treatment of disorders mediated by complement activity such as paroxysmal nocturnal hemoglobinuria (PNH), according to a study published in Blood Advances.  Dysregulation of the alternative complement pathway has been implicated in a number of disorders, including inflammatory conditions. Much effort…

Coagulation factor VIII

The Challenge of Diagnosing Acquired Hemophilia A in Adults

Hemophilia A is characterized by abnormally low factor VIII (FVIII) activity; common symptoms include bleeding in various parts of the body, such as the joints and the muscles. While hemophilia is typically diagnosed in childhood, acquired hemophilia A (AHA) is more commonly diagnosed in adults. As its name suggests, this condition is acquired rather than congenital.…

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