Researchers have discovered that serum Krebs von den Lungen-6 (KL-6) level may be a useful biomarker of disease progression in idiopathic pulmonary fibrosis (IPF), as published in Scientific Reports. IPF is a progressive fibrosing interstitial pneumonia that carries a poor prognosis, with a median survival of only 3 to 5 years. Currently, physiological parameters obtained…
Researchers reported that there was still a disparity between objective and patient-based measures of chronic rhinosinusitis in individuals with cystic fibrosis (CF) who were treated with highly effective modulator therapy, and published their findings in the International Forum of Allergy & Rhinology. One of the keys to boosting the quality of life in patients with…
Scientists have proposed the eradication of mast cells as a therapeutic strategy to fight against mast cell activation disorders.
Researchers reported the case of a patient who had acute mast cell leukemia preceded by a malignant mediastinal germ cell tumor and published their findings in Cancer Management and Research. Systemic mastocytosis (SM) occurs when mast cells invade the bone marrow as well as other organs in the body. Mast cell leukemia is a subtype…
We explore 2 case studies of pediatric patients diagnosed with Alagille syndrome who presented with dyslipidemia and discuss what we can learn from them.
Genomic profiling for cholangiocarcinoma and other cancers demonstrates significant evidence-based benefits, but faces practical hurdles.
During the height of the COVID-19 pandemic, physicians reported treating new cases of myasthenia gravis post-infection.
People with rare diseases who live in the United States have a poor health-related quality of life and experience significant stigma, according to a study published in the Orphanet Journal of Rare Diseases. A rare disease in the United States can be defined as any disease in which the prevalence is less than 200,000 cases.…
Researchers discovered that the modified aspartate aminotransferase-to-platelet ratio index score (mAPRI) is a highly specific and noninvasive tool for the diagnosis of cystic fibrosis-related liver disease (CFRLD), as published in Clinical Transplantation. Despite the fact that liver disease is a significant cause of morbidity and mortality in patients with cystic fibrosis (CF), there is still no…
We explore the controversy around whether sickle cell carriers are at a higher risk of developing health complications.
