Juliette Siegfried, MPH

Juliette Siegfried, MPH

Juliette Siegfried, MPH is a biomedical writer, editor, and translator who has worked in health communications for over 30 years. After working as a health communications specialist for the National Institutes of Health in Bethesda, Maryland, and its contractors, Juliette moved to Madrid, Spain, and established ServingMed.com, a small medical editing, writing, and translating business for hospitals, universities, research foundations, and individual health care professionals who seek to publish their work in English. In 2010, Juliette moved with her family to the Netherlands, where she currently manages a team of 3 writer-editor-translators and serves an expanded clientele around the globe.

All articles by Juliette Siegfried, MPH

Study Favors Somatostatin Receptor-Directed Imaging for MTC Treatment

The use of somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) is better than computed tomography alone in terms of assisting with therapeutic decision-making in patients with medullary thyroid carcinoma (MTC), according to a new study published in Endocrine. The researchers reported switching between surgery and systemic treatment with tyrosine kinase inhibitors (TKIs) in over…

Molecular Genetic Testing: An Important Component in Diagnosing ALGS

Researchers identified a previously classified “idiopathic” gene that is responsible for neonatal/infantile cholestasis, including in patients with Alagille syndrome (ALGS), and presented their results at the 54th annual European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) meeting. The study credits advances in molecular genetics, particularly the use of next-generation sequencing in testing candidate genes…

Cannabidiol

Cannabidiol and Cannabigerol Effectively Inhibit CCA Cells

Cannabidiol (CBD) and cannabigerol (CBG) have antitumor activity on cholangiocarcinoma (CCA) in vitro, according to a new study published in Biomolecules. The researchers found that each compound uses a distinct cell death pathway to inhibit CCA. “We found that both CBD and CBG were effective in inhibiting cholangiocarcinoma cells in vitro in a dose-dependent manner,…

A Rare Case of Pompe Disease and Congenital Myasthenic Syndrome

Researchers reported a rare case of a 4-year-old girl with co-occurrence of Pompe disease and congenital myasthenia syndrome type 5. The case report, published in Cureus, described good results from whole-exome sequencing for an early diagnosis and subsequent alglucosidase alfa enzyme replacement therapy (ERT), which is currently the only approved treatment for Pompe disease. “Early…

nsaids

NSAID Use in Hemophilia Linked With Low Risk of Adverse Events

Most studies on the use of selective and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with hemophilia show no significant increase in bleeds or cardiovascular events with the use of these medications, according to a new review published in Blood Reviews. The authors noted that older studies with a high risk of bias and other…

bronchial tree

One Session of Autogenic Drainage Reduces Peripheral Resistance in CF Study

One session of autogenic drainage can enhance peripheral clearance in children with cystic fibrosis (CF), particularly those with bronchial congestion, according to a study published in BMC Pulmonary Medicine. The researchers noted that the technique did not modify peripheral resistance in children without congestion. “In a long-term comparative study in adolescents with CF, autogenic drainage…

Kappa Index Useful for Diagnosing Multiple Sclerosis

Kappa index, or K-index, can be a useful tool for diagnosing multiple sclerosis (MS) and predicting the risk of evolution to MS in patients with clinically isolated syndrome (CIS), according to a new study published in Clinical Immunology. The researchers determined several cut-off values for the K-index to achieve optimal sensitivity and specificity as compared…

Stroke

Prophylactic Hydroxyurea Linked With Reduced Stroke Risk in SCD

Prophylactic use of hydroxyurea in children with sickle cell disease (SCD) significantly reduces middle cerebral artery blood velocity as assessed by transcranial doppler ultrasound (TCD), thus potentially reducing stroke risk in these patients, as published in the Journal of Clinical Medicine. The researchers provided further evidence supporting the use of hydroxyurea in patients with SCD,…

screening scale

New Therapies Lead to the Need for a Broader View of HAE Symptoms and QoL

A targeted literature review and interviews with key opinion leaders (KOLs) have determined that new prophylactic treatments for hereditary angioedema (HAE) have increased the importance of more broadly assessing symptoms and quality of life in patients with the disease. The review, published in the Orphanet Journal of Rare Diseases, noted that previously, the focus had…

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