Juliana Campos, PhD

Juliana Campos, PhD

Juliana Campos (MSc, PhD) is a freelance writer with a strong scientific background in biomedicine, cellular and molecular biology, and biochemistry, and a keen interest in science communication.

All articles by Juliana Campos, PhD

Venous thrombosis

SERPINA1 Variations Linked With Venous Thromboembolism in AATD

A population-based Swedish study showed that homozygosity or compound heterozygosity for variants associated with severe alpha-1-antitrypsin deficiency (AATD) is linked to venous thromboembolism (VTE). From a total of 40 homozygous or compound heterozygous individuals, 10 had incident VTE. The authors identified 84 SERPINA1 variants (21 synonymous, 62 missense, and 1 loss-of-function) in 28,794 individuals from…

Adrenal gland

MTC With MEN2A Metastasizing to Pheochromocytoma: A Rare Case

A rare case of a patient with multiple endocrine neoplasia type 2 (MEN2) with medullary thyroid carcinoma(MTC) metastasizing to adrenal pheochromocytoma was reported in China. “The similar neuroendocrine histological appearance of pheochromocytoma and MTC made the pathological diagnosis of a metastatic MTC difficult, especially when the metastatic foci was very limited,” said the authors of…

Glucose molecule

Targeting miR-378 as a New Strategy to Mitigate DMD Symptoms

The loss of the microRNA miR-378 improved the dystrophic phenotype in a mouse model (mdx) with Duchenne muscular dystrophy (DMD), according to a new study published in Scientific Reports. “The most important finding is that we identified miR-378 as a factor that regulates not only muscle-related dysfunctions, as we showed previously, but also metabolic disturbances…

cardiopulmonary system

ROCK1 and ROCK2 Play Independent Roles in the Pathogenesis of PAH

The Rho kinases ROCK1 and ROCK2 have nonoverlapping roles in pulmonary arterial hypertension (PAH), according to a new study published in Biochemical and Biophysical Research Communications. “Our study supports the further elucidation of ROCK1 and ROCK2 functions, and the development of selective ROCK inhibitors as potential novel therapeutic agents in [pulmonary hypertension] and related pulmonary…

chromosome

Researchers Find Cytogenetic Differences Between Gastric and Nongastric GISTs

Researchers from Norway uncovered cytogenetic differences between gastric and nongastric gastrointestinal stromal tumors (GISTs) in their analysis of more than 300 GIST samples. “Based on the examination of such a large dataset, we were able to elucidate the roles of individual chromosomes in the pathogenesis of tumors with different genotypes and sites of origin, and…

doctor and patient

Risk Stratification Tools for PAH Remain Underused in Clinical Practice

Pulmonary arterial hypertension (PAH) risk assessment tools remain underused, despite the variety currently available, researchers report in the Pulmonary Circulation journal. “Routinely, clinicians assess patients during clinical visits based on their gestalt which may or may not incorporate patient’s history, laboratory and ambulatory tests, right heart catheterization hemodynamics, and imaging studies into decision making,” explained…

test tube

Biliary Epithelial Cells Offer Potential as Regenerative Therapy for ALGS

Biliary epithelial cells (BECs) from human livers were able to restore biliary structure and function in a mouse model of biliary disease, as published in Cell Stem Cell. “This demonstration of a human cell therapy leading to the rescue of animals from biliary disease offers future clinical therapeutic opportunities for the use of these cells…

cognition assessment

Myasthenia Gravis Associated With Cognitive Impairments

Patients with myasthenia gravis (MG) may suffer from a variety of cognitive disorders, according to a recent meta-analysis published in the International Journal of Neuroscience. “Our results confirmed that patients with MG may have declines in cognitive function, including in the domains of language, visuospatial function, information processing, verbal immediate and delayed recall memory, visual…

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