Juliana Campos, PhD

Juliana Campos, PhD

Juliana Campos (MSc, PhD) is a freelance writer with a strong scientific background in biomedicine, cellular and molecular biology, and biochemistry, and a keen interest in science communication.

All articles by Juliana Campos, PhD

BRD9 as a Novel Therapeutic Potential for GIST

The bromodomain-containing protein 9 (BRD9) was identified as a key molecule in the progression of gastrointestinal stromal tumors (GISTs), according to researchers from the Hospital of Jilin University, Changchun, China. The study was published in the journal Cell Death & Disease. BRD9 inhibition can be considered as a new therapeutic strategy in GISTs, used as…

SERPINA1 Genotypes Pose Different Risks for Liver Pathology

SERPINA1 genotype determines the severity of alpha-1 antitrypsin deficiency (AATD) and the serum levels of alpha-1 antitrypsin (AAT), concluded a new study published in the International Journal of Molecular Sciences. It also influences the risk of hepatocellular carcinoma (HCC) in patients with liver cirrhosis. SERPINA1 provides instructions for the production of AAT, a protein mainly…

Case Report: A Rare Co-occurrence of ALGS and Von Willebrand Disease

A 17-year-old Indian female presented with co-occurring Alagille syndrome (ALGS) and von Willebrand disease (vWD). The likelihood of having both genetic conditions is extremely low, according to a case report published in the South African Journal of Child Health. The patient was diagnosed with ALGS during infancy. The diagnosis was based on phenotypic criteria (ie,…

Male Sex Associated With Poor Prognosis in GIST

A new retrospective study emphasized the importance of preoperative evaluation and frequent postoperative follow-up of gastrointestinal stromal tumor (GIST) patients. This study was published in the journal Medical Science Monitor. This close monitoring is particularly important in older male patients and patients with malignant comorbidities. “There is an association between tumor location, size, length of…

Treprostinil Sodium Has Similar Safety Profiles in Pediatric and Adult PAH

A new retrospective study concluded there was no significant difference between the safety profile of treprostinil sodium (Remodulin®) in pediatric and adult pulmonary arterial hypertension (PAH) populations. The results of the study conducted by Habaradas et al are being presented at the Chest 2021 Annual Meeting, which is being held virtually from October 17 to…

New LOPD Conceptual Model Identifies Key Symptoms and Functional Impacts

Researchers have developed qualitative interviews that identified the most frequent and relevant symptoms in patients with late-onset Pompe disease (LOPD). The new conceptual model also evaluated the functional impact of LOPD on patients’ daily living. Patients described these as the most common and disquieting symptoms: fatigue (92%), site-specific muscle pain (69%), muscle weakness in the…

IPF exercise

Dedicated ILD Clinic Care Improves the Monitoring of Patients With IPF

A dedicated interstitial lung disease (ILD) clinic improves the care provided to patients with idiopathic pulmonary fibrosis (IPF), according to a recent study conducted by Gross et al. Improvements were observed even in clinics located in small healthcare systems, regardless of their association with a tertiary care center. The results of the study will be…

Splicing Mutations as Potential Diagnostic Targets for ALGS

Alternative splicing has been implied in the development and progression of pediatric liver diseases such as Alagille syndrome (ALGS), according to a new review published in Frontiers in Molecular Biosciences. The current knowledge on ALGS etiology estimates that most patients (94%) have variants of the JAG1 gene. A smaller percentage (1%-2%) of patients present alterations…

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