Jovana Nikolic, MD

Jovana Nikolic, MD

Jovana Nikolić, MD, is a medical/science writer from Serbia. Throughout her studies at the University of Nis, she developed a great interest in scientific research in the field of Immunology, Hematology, and Neurobiology.

All articles by Jovana Nikolic, MD

group of people

Case Series: Relatives With ALGS Exhibit Diverse Phenotypes and Disease Severity

A highly variable phenotype and differing disease severity has been reported in 4 family members with Allagile syndrome (ALGS). The case series was published in the International Journal of Pediatrics and Child Health. The proband, the third-born child in the family, presented with a globular abdomen, loss of appetite, and poor growth at 18 months…

online questionnaire

Electronic PRO System Shows High Feasibility and Performance in Patients With PNH

An electronically gathered patient reported outcomes (ePRO) system customized for paroxysmal nocturnal hemoglobinuria (PNH) and aplastic anemia (AA) and may be a feasible data collection and patient guidance solution in light of high adherence, satisfaction, and performance, according to an article published in the journal Annals of Hematology. For the purpose of this single-center study,…

Shoulder pain

Study Supports the Use of Efanesoctocog Alfa for Bleeding Prevention in Hemophilia

Treatment of hemophilia A with a weekly dose of efanesoctocog alfa may provide superior bleeding prevention compared to factor VIII prophylaxis, as well as normal to near-normal factor VIII activity and improvements in physical health, pain, and joint health, according to an article recently published in The New England Journal of Medicine. For the phase…

bone marrow extraction

Morphologic Assessment of Bone Marrow Biopsy May Help Diagnose LSDs

A morphologic assessment of bone marrow biopsy may be a valuable indicator of lysosomal storage disorders (LSDs), which include lysosomal acid lipase deficiency (LAL-D) and Pompe disease, when paired with associated clinical, hematological, and biochemical parameters, according to a study recently published in the Indian Journal of Pathology and Microbiology. For the purpose of this…


C1 Inhibitor Deficiency May Increase Coagulation and Venous Thrombosis

Increased venous thrombosis has been detected in C1 inhibitor (C1INH)-deficient mice, while contact pathway-initiated thrombin generation may be increased in both mice and people with hereditary angioedema (HAE) caused by C1 inhibitor efficiency (C1INH-HAE), according to a new study published in the journal Blood. For the purpose of this study, the authors examined 19 patients…

sick boy sleeping

Pain May Be Correlated With Sleep Disturbances in Pediatric Patients With SCD

Pain interference is associated with both sleep disturbance and sleep-related impairment in pediatric patients with sickle cell disease (SCD), according to a recent study published in Pediatric Blood & Cancer. The researchers performed a cross-sectional survey of 105 patients aged 8 to 17 years with SCD using Patient-Reported Outcomes Measurement System (PROMIS) pain interference, sleep disturbance,…

elderly man with doctor

Analysis Finds High Incidence of Avapritinib-Related Adverse Events in Elderly Men

A postmarketing pharmacovigilance analysis of avapritinib, a medication used in the treatment of systemic mastocytosis (SM), discovered that elderly male patients were at an increased risk of experiencing serious adverse events related to treatment. The study was published in the British Journal of Clinical Pharmacology. The study authors extracted 3120 avapritinib-related reports submitted to the US…

FDA approval

Sanofi’s Sutimlimab Approved by FDA for CAD Patients Without Recent Blood Transfusions

Sutimlimab-jome (Enjaymo®), the only available hemolysis treatment for adults with cold agglutinin disease (CAD), has received an additional indication from the US Food and Drug Administration (FDA) for use in patients without a history of blood transfusions. The humanized monoclonal antibody, which is designed to selectively target and inhibit the classical complement pathway-specific serine protease…

DNA genetics

Study Identifies Novel Genetic Mutations Contributing to the Development of AATD

Five rare genetic variants of the SERPINA1 gene, including 4 previously unknown mutations, might be associated with the development of alpha-1 antitrypsin deficiency (AATD), according to a new study published in Respiratory Research. For the purpose of this study, the researchers recruited 6 patients with moderate to severe AATD from the outpatient clinic of the…

Gene mutation illustration

Report Demonstrates Inheritance of His90Asp Variant Among People With hATTR

Three family members diagnosed with hereditary transthyretin amyloidosis (hATTR) have been identified as carriers of an autosomal dominant His90Asp variant, according to a study recently published in the Canadian Journal of Neurological Sciences. The study authors reported on a woman aged 74 years who presented with early satiety, postural hypotension, episodes of intractable vomiting, fluctuating…

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